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Rank: Advanced Member  Groups: Registered
Joined: 12/4/2009 Posts: 331 Location: South London
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Hi there, Just got a copy of a recent bloodtests. RA has been pretty active up until these bloodtests were done and things feel like they have died down a bit. But I am wondering does the RF and Anti ccp ever come down to they keep rising ? or is it an indication of how actuve the disease is? I just revising this as I have just been told that anticcp confirms the diagnoses of RA and high levels can indication aggression of disease of disease but doesnt mean its probable more like a possiblitiy. Anyway still want to know if anyones RF and anticcp have gone down. Many thanks 
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Rank: Advanced Member  Groups: Registered
Joined: 12/6/2009 Posts: 84 Location: Northern Ireland
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Hi Yes mine have just recently come down, when I got meds that agreed with me and worked well all my blood results started to go in the direction of nearly normal. This took quite a while to happen. Joy
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Rank: Advanced Member  Groups: Registered
Joined: 12/3/2009 Posts: 2,237 Location: nr Southampton
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hi
I do know a little about this.
First things first- not everyone has RA that shows in the bloods. If that anti-CCP is positive it is almost certain that you have RA.
the more positive it is (the higher the result) says something about the severity of it.
I have no idea if this one goes down at all. Mine is too high for them to measure (not a competition I really wanted to win ) but I know it has never been in measurable range- even when I have been quite "well".
I do know that the RF is again an indication of how nasty that RA is. If you have sero positive RA (there is a sero negative sort) the RF will be raised. If you are really poorly with it- it will be much higher- if it is well controlled it can get near normal in some patients.
I know one of the tests they do when you are on Rituximab is the RF one to see if has come down in response to the drug in sero positive patients.
Mine RF when doing well gets to about 400 and is normally around the 700-800 level, once it went to 270 and once it went over 900. This is severe RA though- only 3% of RA patients get this.
To understand blood tests more generally try this site- it is quite general but gives a guide.
http://www.labtestsonline.org.uk/
I hope this has helped a little
Jenni xxhow to be a velvet bulldoser
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Rank: Advanced Member Groups: Registered
Joined: 12/3/2009 Posts: 2,237 Location: nr Southampton
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Hi!
You have me interested now! I have found that in some patients the anti-ccp does go down with effective treatment in some cases- here is a brief table of study results showing what drugs patients have been taking and whether it effected their anti-ccp results:
http://rheumatology.oxfo...ntent/full/45/1/20/TBL1
it is from this article which is a bit on the scientific wordy scale but I managed most of it-
http://rheumatology.oxfo...gi/content/full/45/1/20
it is interesting to me anyway!!!!!
Jenni xhow to be a velvet bulldoser
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Rank: Advanced Member Groups: Registered
Joined: 12/3/2009 Posts: 2,237 Location: nr Southampton
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ps. they did tell me once that below 4.9 anti ccp is "normal"how to be a velvet bulldoser
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Rank: Advanced Member  Groups: Registered
Joined: 12/8/2009 Posts: 124 Location: Wolverhampton
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Jenni, how does one work out the crp? Mine is now 15 which is high for me.
Thanks, Nina x
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